实验性诱导营养不良对鸡脑部抑郁和情绪中等以及血液影响的生物化学作用
DOI:
https://doi.org/10.18686/zhfnc.v1i2.71关键词:
鸡；营养不良；脑功能；血液指数；贫血；CBC摘要
背景：营养缺乏和营养不良会引起周期性嗜睡、情绪低落和贫血。因此，在本研究中，我们通过实验诱导鸡营养不良，以跟踪鸡的脑功能和贫血状况（血液指数）。材料和方法：本研究以两组60只一天龄的雏鸡为研究对象，这些雏鸡喂食商品开食料10天，然后平均分成两组，饲养6周。第一对照组在生长期和育成期饲喂商品生长料和育成料，而第二试验组在生长期和育成期持续饲喂黄玉米。所有雏鸡在六周内每周称重一次，以记录体重差异。每两周从每组的10只雏鸡中采集全血样和脑匀浆，以评估脑组织匀浆参数、白细胞计数差异、全血细胞计数和血液指数。结果：比较两组雏鸡的脑组织匀浆发现，缺食组的乙酰胆碱酯酶（AChE）和总抗氧化能力（TAC）在整个饲养过程中显著增加，而肿瘤坏死因子-α（TNF-α）在缺食组第二周和第四周后增加，第六周后两组无显著差异。对照组的谷胱甘肽过氧化物酶（GPx）和超氧化物歧化酶（SOD）在整个实验期间都明显增加，而全血细胞计数（CBC）和细胞差异计数显示，食物缺乏组的白细胞（WBCs）在整个实验期间都明显增加、嗜酸性粒细胞浓度在缺食组两周和四周后明显升高，六周后两组差异不明显；淋巴细胞在对照组第二周后明显升高，四周后差异不明显，六周后缺食组则明显升高。缺食组的中性粒细胞计数在第六周后明显偏高，单核细胞浓度在缺食组中两周后明显升高，四周后无明显差异，在对照组中六周后明显升高。嗜碱性粒细胞和分段中性粒细胞在食物缺乏组两周后明显增加，两组在四周和六周后差异不明显。此外，对照组的血红蛋白（Hb）、红细胞（RBCs）、包装细胞容积（PCV）、平均体细胞容积（MCV）和血小板计数在整个持续时间内均显著增加，对照组的平均体细胞血红蛋白（MCH）和平均体细胞血红蛋白浓度（MCHC）在四周和六周后显著增加。结论：营养不良会对大脑功能和血液参数产生很大影响。
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